About Alzheimer's
Alzheimer's is a progressive, fatal neurodegenerative disease and the most common cause of dementia.
The disease is caused in part by a spiraling cascade initiated by the generation of a sticky form of amyloid-beta (Abeta), leading to progressive destruction of myelin (the nerve cell sheath), accumulation of toxic deposits called plaques, and nerve cell death in the brain.
Alzheimer's causes profound structural changes in the brain, resulting in severe and progressive cognitive decline.
Drugs that effectively and safely inhibit the Alzheimer's disease cascade are anticipated to reverse Alzheimer's progression.
